Masato Yamamoto, MD, PhD, will hold a presentation on Development of Infectivity-Selective Oncolytic Adenoviruses on Monday, Dec. 11, noon to 1 p.m. in the sixth floor conference room of the Department of Orthopaedics, 110 S. Paca-Pratt Building.
Yamamoto is professor and director of Basic and Translational Research Labs in the Department of Surgery at the University of Minnesota. His lab is one of the leading labs in the field of development of adenovirus vector-based cancer therapeutics. They have recently developed a novel vector production method that enables generation of high-diversity adenoviral library for high throughput screen targeting many motifs. They have successfully applied replication competent adenoviruses to therapeutic gene transfer at high level in the cancer cells.