Research posts displayed by category

Sentinel Study Seeking Volunteers

In October, we focus on women’s health, and, in light of that, consider being part of a study.

Did you know that microbes residing in the vagina are critical to women’s reproductive health and play a key role in preventing disease that can lead to infertility and cancer?

Be a part of the Sentinel Study, co-led by Associate Professor Mary Regan, PhD, RN, which will help researchers understand how the vaginal environment can protect women’s health and subsequently develop interventions.

The Sentinel Study is seeking participants Mondays, 11:15 a.m.-12:30 p.m.; Tuesdays, 11:45 a.m.-12:30 p.m.; and Wednesdays, noon-1 p.m. Come to the University of Maryland School of Nursing lobby for more information about the study and to participate. Participants will be compensated $20 for completion of the study activities. Call 410-706-3200 for details.

  
Giordana Segneri Bulletin Board, ResearchOctober 18, 20170 comments
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Engaging Hepatitis C Patients to Improve Research Methods

When I joined the School of Pharmacy in 2014, my primary focus was on teaching pharmacy management and developing research skills in the area of economic evaluation. As a faculty member in the Department of Pharmacy Practice and Science (PPS), I enrolled in the PhD in Pharmaceutical Health Services Research (PHSR) program at the school to become a pharmacoeconomist and build cost-effectiveness studies. However, I enrolled into the program at a time when the culture in research was beginning to shift, primarily because of extraordinary PHSR professors who knew that researchers could do a much better job systematically including the patient voice in our work.

Evaluating cost-effectiveness of hepatitis C treatments

Like any other graduate student, I dove into the literature around the new treatments for the hepatitis C virus (HCV). With help from Julia Slejko, PhD, assistant professor in PHSR, and C. Daniel Mullins, PhD, professor and chair of PHSR, I developed my first cost-effectiveness study for HCV treatments, but I fell into the trap of focusing on traditional methods that did not include patients.1 Although it was good experience for me to gain while learning this field, I knew there was much more to do.

Engaging patients to improve methods

After submitting my economic model, I spoke informally with Susan dosReis, BSPharm, PhD, and Eleanor Perfetto, PhD, MS, both professors in PHSR, about the lack of patient input in all of the HCV cost-effectiveness studies that I had reviewed. Without hesitation, Perfetto smiled and said, “There is your next paper.” So, we went to work. We systematically reviewed economic studies for HCV treatments and found that the inclusion of the patient voice has been limited in this area, to say the least.2

Submission to PCORI: It takes a village

One of the key lessons that I’ve learned over the past year is that most good research proposals require a team effort, and all researchers are influenced by the company they keep. With several faculty in the department having success with their contract submissions to the Patient-Centered Outcomes Research Institute (PCORI) – facilitated, in part, by the creation of the PATIENTS Program – a culture of authentic, patient-centered research has weaved throughout the school.

I recently had an opportunity to become the director of operations with the PATIENTS team, where I learned firsthand what it meant to “continuously engage” patients in every step of the research process.3 The natural progression for me was to submit a Pipeline to Proposal (P2P) Tier A award to PCORI, which would fund the work necessary to build relationships with patients in the West Baltimore community where the School of Pharmacy is located. I pitched an idea to leverage the Community Engagement Center at the University of Maryland, Baltimore (UMB) to work with underserved patients as advisors to our research to Shyamasundaran Kottilil, MD, PhD, professor of medicine and renowned HCV clinician and researcher at the School of Medicine’s Institute of Human Virology (IHV). He immediately came on board.

With the support of Kottilil; Ashley Valis, executive director for strategic initiatives and community engagement at UMB; and Mullins, as director of the PATIENTS Program, our proposal was created and, fortunately, won over the reviewers at PCORI.

Now the real work begins

In our P2P, we aim to engage underserved HCV patients to inform and improve comparative effectiveness research for HCV interventions. We also plan to develop a blog that will target patients and researchers to disseminate our work in a way that is meaningful to both audiences. We want to bring patients, clinicians, and researchers to the same table to discuss research questions related to HCV treatment that matter most to patients. This multi-stakeholder approach will help us develop another research proposal that might be of interest to funding agencies such as PCORI, the National Institutes of Health, or the Food and Drug Administration. We’re excited to get started and can’t wait to see how the results of our work might impact future studies.

Joey Mattingly, PharmD, MBA, assistant professor in PPS and PHSR graduate student

References

1 Mattingly TJ, Slejko JF, Mullins CD. Hepatitis C Treatment Regimens Are Cost-Effective: But Compared With What? Ann Pharmacother. 2017; online: July 1, 2017. doi:10.1177/1060028017722007.

2 Mattingly TJ, Perfetto EM, Johnson S. Engaging hepatitis C infected patients in cost-effectiveness analyses: A literature review. Hepatology. August 2017. doi:10.1002/hep.29482.

3 Mullins CD, Abdulhalim AM, Lavallee DC. Continuous Patient Engagement in Comparative Effectiveness Research. JAMA. 2012;307(15):1587-1588.

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Joey Mattingly ResearchOctober 18, 20170 comments
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School of Nursing’s Colloca Writes About Nocebo Effect

To provide the public with a better understanding of recent groundbreaking research on the nocebo effect, Luana Colloca, MD, PhD, associate professor, University of Maryland School of Nursing, has written an article, “Nocebo Effects Can Make You Feel Pain,” published in Science magazine.

The nocebo effect occurs when a person has a negative expectation of a treatment outcome, leading to adverse effects that otherwise might not occur. Although patient response often can be influenced by expectations, Colloca and her research team discovered that negative reactions to treatments go beyond psychological responses and involve neurobiological mechanisms. Building on Colloca’s work and other lab research, a recent study by Alexandra Tinnermann and colleagues at the University Medical Center in Hamburg, Germany, showed that when a patient expects to experience more pain, there is an activation of the spinal cord leading to increased pain perception.

“If a patient believes the pain is getting worse, even while going through treatment, there may be an increase of the activation of pain facilitatory pathways involving the spinal cord. Tinnermann’s study is the first neurobiological demonstration that shows expectations can change brain nociception processing and make people feel more pain,” Colloca said. “This and other nocebo studies are important because they suggest that the nocebo phenomenon can change the patient response to pain sensations and painkillers.”

Often, successfully overcoming an ailment can depend on past experiences with treatment. Additionally, information provided during the consent process and in the context of patient-clinician communication may trigger nocebo responses. Nocebo effects can contribute to perceived adverse effects and influence clinical outcomes and whether or not a patient adheres to prescribed medication. Nocebo effects should be avoided during clinical trials and practices, according to Colloca. Instead of concealing information related to side effects, a better approach is to minimize nocebo response by tailoring patient-clinician communication to balance truthful information about adverse events with expectations of outcome improvement, exploring patient treatment beliefs and negative therapeutic history, and paying attention to treatment descriptions.

You can read Colloca’s article on the Science magazine website.

  
Kevin Nash Bulletin Board, Collaboration, Education, People, Research, UMB News, University LifeOctober 17, 20170 comments
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Digital-Library

Meet Your School’s Liaison Librarian

Each school at UMB has a dedicated research, education, and outreach librarian, which ensures the best possible service for faculty, staff, and students.

What can your liaison librarian do?

  • 
Consult with you to assist with literature searching and research.
  • Collaborate on comprehensive literature searches for systematic reviews.
  • 
Teach citation management using RefWorks, EndNote, and other systems.
  • Gather data to measure your individual, group, or departmental research impact.

Visit the Research Connection page to see all the ways your librarian can help.

Who is you school’s liaison librarian? Look here.

  
Everly Brown Collaboration, Education, People, Research, University Life, USGAOctober 12, 20170 comments
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The President’s Message

Check out the October issue of The President’s Message. It includes Dr. Perman’s column on the Catalyst fundraising campaign, a look ahead to Founders Week and Derreck Kayongo’s Politics and Policy presentation, a recap of the quarterly Q&A, a safety tip for pedestrians, and a roundup of student, faculty, and staff achievements.

  
Chris Zang ABAE, Bulletin Board, Collaboration, Community Service, Contests, Education, For B'more, People, Research, Technology, UMB News, University LifeOctober 10, 20170 comments
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Submit Your Wishes to the HS/HSL Library Genie

How can the Health Sciences and Human Services Library better meet your needs?

Would you like to see the library’s space designed differently? Are there any new technologies you would like to see? Are there additional resources and services you would like provided?

Now is the chance to make your wishes known. The Library Genie is accepting wishes through Oct. 31. Submit three Library Wishes to the Library Genie today!

All wishes are anonymous, but if you’re willing to talk about them, please include your name and email address.

Thanks for your input, and happy wishing!

  
Everly Brown Collaboration, Education, People, Research, Technology, University LifeOctober 4, 20170 comments
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Seminar with Dr. Laura Stapleton Will Explore Research Methods

Laura Stapleton, PhD, MEd, professor in Measurement, Statistics, and Evaluation (EDMS) in the Department of Human Development and Quantitative Methodology at the University of Maryland, College Park (UMCP), will hold a research seminar Oct. 19 at 12:15 p.m. in Room 4E26 at the School of Social Work.

In this hands-on presentation, suggested steps for questionnaire development and validation will be discussed and participants will be challenged to critique example items and undertake qualitative validation processes. Quantitative validation processes also will be discussed and a general outline of steps in the creation and validation process will be provided.

If you wish to attend, please RSVP to Jen Canapp by Oct. 16.

In addition to her UMCP professorship, Stapleton serves as associate director of the research branch of the Maryland State Longitudinal Data System Center. She joined the faculty of EDMS in the fall of 2011 after being on the faculty in Psychology at the University of Maryland, Baltimore County, and in Educational Psychology at the University of Texas in Austin. She also serves each year on the faculty of the National Center for Education Research-funded Summer Research Training Institute on Cluster-Randomized Trials at Northwestern University in Evanston, Ill.

Before earning her PhD in Measurement, Statistics, and Evaluation from UMCP in 2001, she was an economist at the Bureau of Labor Statistics. Subsequently, she conducted educational research at the American Association of State Colleges and Universities and as associate director of institutional research at UMCP.

  
Jen Canapp Collaboration, Education, Research, UMB NewsOctober 3, 20170 comments
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Applications Sought for Faculty Global Health Project Grants

The Center for Global Education Initiatives is seeking proposals for grant funding it provides for UMB faculty members to lead interprofessional global health projects overseas.

The grant seed funding is intended to promote collaboration among professions and schools. This year, the center will award up to five projects for implementation in the summer of 2018.

These grants can help advance faculty members’ global research interests and involve UMB students in your work. Once faculty projects are selected and announced, there will be a competitive application process for students to participate.

Applications are due by Oct. 16. For instructions and more details on how to apply, please visit the center’s faculty grants web page.

  
Heidi Fancher Bulletin Board, Collaboration, Education, Research, UMB NewsSeptember 29, 20170 comments
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UMB-CURE-Scholars

Mentors Needed for UMB’s CURE Scholars Program

The UMB CURE Scholars Program is in need of UMB students, faculty, and staff to volunteer as mentors during the 2017-18 school year.

Consider becoming a mentor and nurturing the career of a future health care professional. Your knowledge and experience can make a huge impact on the life of a middle school student from West Baltimore, and the commitment will not require much of your time.

Mentors will be expected to:

  • Commit to at least one year of mentorship, with contact at least once a week or bi-weekly.
  • Assist their mentee with the transition from student to professional, supporting them in decisions (such as choosing the best high school or college).
  • Allow their mentee to shadow them at work or accompany them to a meeting, conference, or seminar.
  • Create goals for their own personal and professional development through participation in this program.

Those interested in becoming a mentor are invited to a Lunch & Learn on Thursday, Oct. 5, at noon in the Office of Procurement (Main Conference Room) in the Saratoga Building.

You can RSVP for The Lunch & Learn here and learn more about the CURE Scholars Program by checking out its web page.

To apply as a mentor, register here.

Do not hesitate to reach out with questions or concerns to Borndavid McCraw, UMB CURE Scholars Program mentoring coordinator, bmccraw@umaryland.edu.

Thank you for your support in cultivating a vibrant mentorship community!

  
Borndavid McCraw ABAE, BikeUMB, Community Service, Education, For B'more, People, Research, University LifeSeptember 28, 20170 comments
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Check Out the New Connective Issues Newsletter

The Connective Issues newsletter for September is available here. Find out about how the Health Sciences and Human Services Library (HS/HSL) is supporting your work on the UMB campus and the expert resources and services it has to offer.

Included in this issue:

*Welcome and welcome back!
*Canvas poster printing available
*The “Library Genie” returns Oct. 1
*Meet your librarian
*HS/HSL Speaker Series
*Tips for students
*Whiteboard project wins votes
*Francine Brady gallery exhibit
*Scan with ease

 

  
Everly Brown Collaboration, Education, People, Research, TechnologySeptember 26, 20170 comments
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Student Teams to Reflect on Global Health Projects in Africa

The UMB Center for Global Education Initiatives invites you to attend a global forum  featuring presentations by student teams that participated in the center’s interprofessional global health projects this summer in Nigeria, Rwanda, Zambia, Botswana, and Liberia.

If you are a student interested in participating in this program in the summer of 2018, you can come to the forum to hear about the student teams’ work and listen to their reflections on the experience.

The forum will be held Oct. 11, noon to 1 p.m., in the Gladhill Boardroom (Room 505) of the Health Sciences and Human Services Library. Go here to register to attend this event.

  
Heidi Fancher Bulletin Board, Collaboration, Education, People, Research, University LifeSeptember 26, 20170 comments
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HS/HSL Adds Canvas Poster Printing Option

The Health Sciences and Human Services Library (HS/HSL) now offers a canvas printing option for fabric posters that have the same great resolution and quality you’ve come to expect from its glossy paper prints.

Canvas is a great option if you need a poster you can fold up in a suitcase or want a more durable poster that can stand up to multiple exhibits and frequent moving and packing.

Compared to the library’s paper option, the lightweight canvas material has a slightly higher brightness rating, a nonshiny matte finish, and very subtle canvas texture. Samples are available for viewing in the first-floor display case at the HS/HSL.

The canvas printing option is available on the print request form for $60 per poster. Please see our poster printing guide for details, suggestions, and the submission form. The library also will provide rigid cardboard carrying tubes upon request.

  
Everly Brown Collaboration, Education, People, ResearchSeptember 26, 20170 comments
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Healthy People Needed for Pain Study

Are you between 21 and 44 and have no history of chronic pain? If so, you might be eligible to participate in a School of Dentistry study investigating the relationship between pain and cognitive function.

As a volunteer, you will participate in a screening session and then two sessions lasting two to three hours involving pain sensitivity testing and the performance of computerized tasks. All records will be kept strictly confidential. For participating, you can earn up to $175.

If interested, email your name and phone number to daslab@umaryland.edu.

PI: David A. Seminowicz (HP-00068647)

  
Mariya Prokhorenko ResearchSeptember 26, 20170 comments
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Dean Delivers State of the School of Pharmacy Address

On Sept. 11, faculty, staff, students, alumni, and officials from across the University of Maryland, Baltimore gathered in Pharmacy Hall to listen as Natalie D. Eddington, PhD, FCP, FAAPS, dean and professor of the University of Maryland School of Pharmacy, delivered her State of the School of Pharmacy Address. The address, which Eddington also presented at the Universities at Shady Grove on Sept. 6, highlighted the school’s recent accomplishments and advancements in its strategic plan areas of pharmacy education, research, practice, community engagement, and pharmapreneurship.

“Great institutions are committed to their strategic plans, and the School of Pharmacy is no exception,” Eddington said. “The latest iteration of our five-year strategic plan was implemented in 2016 and sets forth lofty goals to achieve before its conclusion in 2021. This year’s State of the School of Pharmacy Address provides an opportunity for us to reflect on those goals that we have already realized while offering a glimpse into the future at new initiatives on which we will embark in the years to come.”

Celebrating a milestone year

Eddington began her address with a recap of the School’s recent 175th anniversary celebration, which began in January 2016 and featured events attended by faculty, staff, students, alumni, and friends of the school. The 18-month celebration not only reflected on the school’s history but also highlighted its ambitions for the future, culminating in a once-in-a-lifetime event that honored nine of the school’s most extraordinary alumni as its Founding Pharmapreneurs and heralded the next era of innovation at the School – an era of pharmapreneurism.

“Our goal is to emulate and follow the example set by our nine founding pharmapreneurs, and offer our faculty, students, and staff every opportunity to be innovators of their own,” Eddington said. “Following their lead, the school will move in a direction in the years to come that no other pharmacy school in the country has conceived of – the creation of programs and initiatives focused on pharmapreneurism.”

Advancing academics

Speaking about the School’s leadership in the area of education, Eddington explained that the Doctor of Pharmacy (PharmD) program remains the largest academic program at the school, receiving an average of 1,000 applications for each class of 160 students. She also noted that the School’s two doctoral programs – the PhD in Pharmaceutical Health Services Research (PHSR) and the PhD in Pharmaceutical Sciences (PSC) – continue to attract the best and brightest students, commending the PhD in PSC program’s participation in the Meyerhoff Graduate Fellowship Program at the University of Maryland, Baltimore County, which aims to increase diversity among students pursuing doctoral degrees in biomedical and behavioral sciences. Eight graduate students currently enrolled in the program are Meyerhoff fellows.

Showcasing the expansion of the school’s academic catalog, Eddington highlighted its three online master’s degree programs – the MS in Regulatory Science, MS in Pharmacometrics, and MS in Palliative Care. Led by Mary Lynn McPherson, PharmD, MA, MDE, BCPS, CPE, professor in the Department of Pharmacy Practice (PPS) and executive director for advanced postgraduate education in palliative care at the school, the MS in Palliative Care launched in the spring of 2017 and has enrolled 80 students, including 14 physicians, 25 nurses, 11 pharmacists, six social workers, and two veterinarians. “The diverse careers held by students in the MS in Palliative Care program illustrate the truly interprofessional nature of this field and further support the demand for advanced knowledge in the field,” she said.

Breaking new ground in research

Shifting the focus to research, Eddington spotlighted the school’s integrative approach to drug discovery and development, innovative patient care, and medication outcomes and their economic impact. She reported that faculty, postdoctoral fellows, pharmacy residents, and graduate students at the school were awarded more than $28.1 million in grants and contracts during Fiscal Year 2017 – a 5 percent increase when compared to Fiscal Year 2016.

In addition to highlighting several faculty members who recently received or renewed multimillion-dollar grants with leading funding agencies such as the National Institues of Health and the National Science Foundation, Eddington presented a number of pioneering research initiatives in which the school is involved, including its participation in the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) and a new partnership with the University of California, San Francisco to accelerate the pace of innovation in pediatric drug and device development.

She also explained how interdisciplinary efforts spanning the school’s three departments are helping to combat drug addiction across the nation, including efforts by researchers in PSC to develop a new opioid compound with no abuse liability, work by faculty in PPS to establish criteria for analyzing data from the state’s prescription drug monitoring program to help identify potentially harmful drug interactions and inappropriate prescribing, and initiatives led by researchers in PHSR to help shape state and federal policy surrounding prescription drug abuse and medication quality in long-term care and mental health.

“Nowhere is our focus as a comprehensive school of pharmacy more evident than in our approach to addiction,” she said. “This impressive body of work encompassing our education, research, practice, and community mission areas focuses on one of our nation’s top public health crises and demonstrates our commitment to playing a major role in curbing the dangerous trends of opioid addiction.”

Leading the pharmacy profession

In the area of practice, Eddington reported that faculty in PPS provided care for nearly 23,000 patients across Maryland in a variety of settings, including outpatient clinics, hospital units, and community pharmacies. She spotlighted the recent launch of the Applied Therapeutics, Research, and Instruction at the University of Maryland (ATRIUM) Cardiology Collaborative and congratulated Magaly Rodriguez de Bittner, PharmD, BCPS, FAPhA, professor in PPS and associate dean for clinical services and practice transformation, on being named the inaugural population health fellow with the University of Maryland Medical System, which helped pave the path for the school to partner with the medical system through a contract with its Quality Care Network to provide pharmacy services and case management support to about 125,000 patients.

Partnering with the local community

Underscoring the school’s commitment to engaging with the local community, Eddington spoke about how members of the Patient-Centered Involvement in Evaluating the Effectiveness of Treatments (PATIENTS) program, which empowers patients to ask questions about their health care concerns and actively participate in studies to answer those questions, hosted or participated in 350 community events throughout West Baltimore, reaching 1,500 patients and community members. She also applauded the work of the school’s numerous student organizations, which organized more than 70 events for members of the greater Baltimore community, noting that several of those initiatives were part of national campaigns, including the National Script Your Future Challenge, or recognized with national awards, such as the school’s American Association of Pharmaceutical Scientists student chapter receiving the organization’s 2016 Student Chapter of the Year Award.

Major charitable giving events also were spotlighted during the presentation, including the success of the school’s inaugural online Giving Day and the creation of new scholarships as a result of endowments made by the family of Felix A. Khin-Maung-Gyi, BSP ’83, PharmD, MBA, who founded and served as chair of Chesapeake Research Review before his death in 2014, and Ellen H. Yankellow, BSP ’73, PharmD ’96, president and chief executive officer of Correct Rx Pharmacy Services.

Looking toward the future

To conclude her address, Eddington offered a look into the future at the School of Pharmacy – a future made even brighter with the recent launch of its new initiative in pharmapreneurism.

“As we move into our next 175 years, the School of Pharmacy remains committed to providing our faculty, students, and staff with the tools and resources they need to solve the perennial, long-term problems facing health care, research, and society,” Eddington said. “Exclusive to the School of Pharmacy, pharmapreneurism formalizes this commitment, allowing us to focus on building innovative pharmapreneurial programs that can be incorporated into every facet of the school.”

  
Malissa Carroll Clinical Care, Community Service, Education, Research, UMB NewsSeptember 26, 20170 comments
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