Researchers at the University of Maryland School of Pharmacy (UMSOP) have published an article in Nature Communications focused on characterizing the interaction between nanoparticles and the immune system and the factors that influence therapeutic outcomes.
The collaborative, multidisciplinary effort sheds new light on the complexities of nanoparticle-based therapies and offers a fresh perspective on why so many nanomedicines fail during clinical trials. It was spearheaded by first author Jacob Shaw, recent PhD graduate with the Pearson Lab at UMSOP, and Ryan Pearson, PhD, associate professor of pharmaceutical sciences (PSC) and director of the School of Pharmacy’s Bio- and Nano-Technology Center (BNTC).
The study team included graduate students and postdoctoral fellows from Pearson’s lab, as well as researchers from the labs of Maureen Kane, PhD, professor of PSC and executive director of the School of Pharmacy’s Mass Spectrometry Center, and Jace Jones, PhD, associate professor of PSC and associate director of the Mass Spectrometry Center.
Read the full story on the School of Pharmacy's News Center.